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 After completing his Diplome d'Ingénieure in Strasbourg, France, and his doctorate in Biochemistry with the University of Stuttgart in Germany, Dr. MacKellar began working in 1991 with the University of Edinburgh in Scotland synthesising genetic antivirals against HIV as a post-doctoral research fellow. In 1993, he continued his research in a biotechnology company in Glasgow for more than four years, during which time he also worked for the international journal Human Reproduction and Genetic Ethics of which he is now the editor.

In 1997, he began teaching biological chemistry and bioethics at Queen Margaret University in Edinburgh, returning to Strausbourg in France, in 2001, to work as a senior civil servant with the Bioethics Division of the Council of Europe. In 2003, Dr. MacKellar returned to Scotland as the Director of Research of the Scottish Council on Bioethics. He is a member of a UK National Health Service Research Ethics Committee in Edinburgh and is also a Fellow with The Center for Bioethics & Human Dignity.