Christians are called to live with integrity. Christian healthcare professionals are called to demonstrate integrity by caring for patients in ethical ways that are loving and wise. Such care relies on faith and reason that understands the value of life, the boundaries of health, the legitimate roles of technology, and the meaning of illness, suffering, and death. This understanding carries countercultural implications in healthcare that create ethical disagreements over controversial medical practices. As a result, Christian healthcare professionals must be ready to communicate and act on ethical convictions as they provide compassionate, respectful care for those in medical need. When faced with pressures to cooperate with morally controversial practices, Christian integrity requires conscientious practice that is perceptive and deliberate in avoiding complicity in actions that are contrary to health and Christian ethics. Conscientious practice may be met by opposition and accompanied by moral distress. The task of Christian integrity in healthcare is therefore challenging. It requires love, prayer, wisdom, courage, and endurance. But this task is also joyful, because in loving God and our neighbors by what we do and by what we resist, we experience a clear conscience that delights in God’s will and draw’s strength from his goodness and mercy. This joy is a sign of the blessing of participating in God’s gracious intentions for this world, even when circumstances are awkward, antagonistic, or hostile. Christian integrity in healthcare therefore brings flourishing. For patients, it communicates life, health, comfort, and hope. For Christian health professionals, it brings the peace of an undivided heart that walks by God’s Word, depends on God’s faithfulness, and trusts in God’s power to comfort, guide, and provide in every moment of our need.